Authors: Jean Francois H. Geschwind and Michael C. Soulen
Publisher:  Cambridge University Press – 337 pages
Book Review by: Nano Khilnani

Even as this book consists of just 337 pages, its coverage is broad in the area of diagnosis and treatment cancer, particularly of billiary, chest, colorectal, liver, musculoskeletal, prostate, and renal, and thoracic and vascular cancers.  Below is an overview of its coverage:

  1. Section I – Principles of Oncology
  2. Interventional oncology: The fourth pillar of cancer care
  3. Section II – Principles of Image-Guided Therapies
  4. Principles of radio frequency and microwave tumor ablation
  5. Principles of irreversible electroporation
  6. Principles of high-intensity focused ultrasound
  7. Principles of embolotherapy and chemoembolization
  8. Principles of radioembolization
  9. Principles of intra-arterial infusional chemotherapy in the treatment of liver metastases from colorectal cancer
  10. Imaging in interventional oncology: Role of image guidance
  11. Novel developments in MR assessment of treatment response after locoregional therapy
  12. Section III – Organ-Specific Cancers – Primary Liver Cancers
  13. Assessment and triage of hepatocellular carcinoma
  14. Image-guided ablation of hepatocellular carcinoma
  15. Embolization of liver tumors: Anatomy
  16. Conventional chemoembolization and chemoembolization with drug-eluting beads: Technique and future potential
  17. 90Yttrium radioembolization for hepatocellular carcinoma
  18. Image-guided therapy of intrahepatic cholangiocarcinoma
  19. Section IV – Organ-Specific Cancers – Liver Metastases
  20. Colorectal masses: ablation
  21. Assessment, triage, and chemoembolization for colorectal liver metastases
  22. Radioembolization for colorectal liver metastases
  23. Assessment, triage, and liver-directed therapies for neuroendocrine tumor metastases
  24. Preoperative portal vein embolization
  25. Section V – Organ-Specific Cancers – Extrahepatic Billiary Cancers
  26. Extrahepatic billiary cancer, Stenting, brachytherapy, and photodynamic therapy
  27. Section VI – Organ-Specific Cancers – Renal Cell Carcinoma
  28. Management of small renal masses
  29. Embolotherapy in the management of renal cell carcinoma
  30. Section VII – Organ-Specific Cancers – Chest
  31. Image-guided ablation in the thorax
  32. Section VIII – Organ-Specific Cancers – Musculoskeletal
  33. Percutaneous ablation of painful metastases involving bone
  34. Cementoplasty and musculoskeletal interventions
  35. Section IX – Organ-Specific Cancers – Prostate
  36. Prostate Ablations
  37. Section X – Specialized Interventional Techniques in Cancer Care
  38. Vascular access: Venous and arterial ports
  39. Palliative care and symptom management
  40. CT-guided neurolysis for cancer-related abdominal and pelvic pain
  41. Palliative procedures for ascites and effusion

Interventional oncology has emerged as an important, targeted therapy in cancer care, and this book provides many techniques for incoming and established practitioners.




Jean Francois H. Geschwind, MD is Chairman of Radiology and Biomedical Imaging at Yale University School of Medicine, Radiologist in Chief at Yale New Haven Hospital, and also a Professor of Radiology and Oncology at Yale University School of Medicine. Originally from Paris, France, Dr. Geshwind received his medical degree from Boston University School of Medicine.

He completed his residency training in Diagnostic Radiology at the University of California in San Francisco, and Fellowship in Vascular and Interventional Radiology in 1998 at Johns Hopkins University School of Medicine, where he remained on faculty as the Chief of Vascular and Interventional Radiology since 2002.

Dr. Geschwind is recognized as a key expert in the field of liver cancer and he has focused his research on developing new therapies for this. He is the author or coauthor of more than 400 published manuscripts and abstracts, primarily on subjects dealing with liver cancer. He is also the recipient of numerous national and international awards and grants for his research in this field. As lead or co-investigator on more than 50 clinical trials, Dr. Geschwind’s research has been published in top peer-reviewed journals, including the following journals: Journal of Clinical Oncology, Journal of Radiology, Hepatology, Clinical Cancer Research, Cancer Research UK, and Annals of Surgery.

Michael C. Soulen, MD received his undergraduate degree from Yale and his medical degree from the University of Pennsylvania, and then trained in radiology at Johns Hopkins. After clinical and research fellowships in Vascular and Interventional Radiology at Thomas Jefferson University, he started the interventional oncology program at the University of Pennsylvania, where he is currently Professor of Radiology and Surgery. A prolific author and lecturer, Soulen served on the boards of the Society of Interventional Radiology (SIR), the SIR Foundation, and the Workers Compensation Insurance Organizations (WCIO). He is a fellow of the SIR and of the Cardiovascular and Interventional Radiological Society of Europe (CIRSE)